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Blaschko's lines visible

The lines of Blaschko are a pattern of lines on the skin that represent the developmental growth pattern during epidermal cell migration. The lines are distinguished from other morphological lines of the skin and do not represent vascular, lymphatic or nervous structures. Typically these lines are not visible; however, certain inherited and. Blaschko's lines, also called the lines of Blaschko, named after Alfred Blaschko, are lines of normal cell development in the skin.These lines are invisible under normal conditions. They become apparent when some diseases of the skin or mucosa manifest themselves according to these patterns. They follow a V shape over the back, S shaped whirls over the chest and sides, and wavy shapes on.

Blaschko's Lines - American Osteopathic College of

  1. Blaschko's lines become visible, if the mutation causes, or makes the skin it effects, more susceptible to diseases that alter the pigment of the skin. These lines are consistently S-shaped on the abdomen, V-shaped on the upper spine, perpendicular along the length of the arms and legs, inverted U-shaped on the chest, and follows a more.
  2. What are the Blaschko lines?. Blaschko lines or the lines of Blaschko are thought to represent pathways of epidermal cell migration and proliferation during the development of the fetus.. History of the lines of Blaschko. This concept was first described by the German dermatologist Alfred Blaschko in 1901 at the 7th Congress of German Dermatological Society
  3. One of the subjects developmental biologists are interested in is the development of pattern. There are the obvious externally visible patterns — the stripes of a zebra, leopard spots, the.
  4. The lines of Blaschko are a pattern of lines on the skin that represent the developmental growth pattern during epidermal cell migration. The lines are distinguished from other morphological lines of the skin and do not represent vascular, lymphat..
  5. Blaschko's lines are the molecular evidence of those swirls. Most people will never see their own stripes. As Dr. Blaschko noted, there are dozens of skin conditions that follow these lines, but.
  6. Each person has stripes on their body called Blaschko's Lines. They are only visible under ultraviolet light. Rating: 0 (from 0 votes) 930 views. Related Items blaschko lines body facts science facts stripes on body ultraviolet ray
Blaschko's Lines and Invisible Stripes on Human Skin

Blaschko's Lines Are Human Stripes Visible Under UV Light. Did You Know People Have Invisible Stripes? Learn about the invisible tiger stripes on human skin, called Blaschko Lines. These lines appear under ultraviolet light. www.thoughtco.com Reply. Post reply Insert quotes Share: Twitter Share Link. Home. Humans have stripes, called Blaschko's Lines, that may be observed under a black or ultraviolet light. They don't glow, but instead become visible. They don't glow, but instead become visible. Tooth Whiteners Glow Under Black Ligh

Blaschko's lines - Wikipedi

Video: Blaschko's Lines Skin Lines Contour Dermatolog

Alfred Blaschko, a German dermatologist, first raised awareness to these stripes back in 1901, thus, they are named after him. The lines aren't linked to the muscular, nervous or lymphatic systems in our bodies and they don't correspond to them The Blaschko's lines result from the fact that some of a chimera's skin cells say make darker skin and some say to make lighter skin. When there is a big difference between the two DNA's instructions on how dark to make the skin, then you get obvious Blaschko's lines. If the differences are more subtle, then you might need something extra like.

If a baby’s entire body was tattooed with a grid of

Blaschko lines DermNet N

Blaschko's Lines ScienceBlog

The lines of Blaschko were described by Alfred Blaschko (1858-1922) in 1901. They represent a pattern assumed by many different nevoid and acquired skin diseases on the human skin and mucosae. These lines do not correspond to any known nervous, vascular, or lymphatic structure but represent the developmental growth pattern of the skin German dermatologist Alfred Blaschko is credited with the first demonstration of these lines in 1901. Noun . Blaschko's lines pl (plural only) Lines of normal cell development in the skin, which become visible in certain diseases. Synonyms . lines of Blaschko Blaschko's Lines. The stripes on the human body were first-ever discovered by dermatologist Alfred Blaschko in 1901, and thus the technical name Blaschko's Lines. The lines are invisible in normal conditions, however, there are cases when genetic mutations make the stripes visible

What are Blaschko's lines on our skin? How can you see

  1. patterns follow Blaschko's lines [12,14,25,29]. It is assumed that Blaschko`s lines (BLs) reflect the migration patterns of epidermal cells and subsequent folding of the skin during embryogenesis [30]. Blaschko's lines become visible when an epidermal cell lineage display
  2. ed over 140 patients with linear skin lesions that followed similar patterns. A diagram of the distribution pattern of these lines has since been drawn and is now referred to as the lines of Blaschko. Blaschko's lines follow a V-shape over the upper.
  3. Blaschko's lines: strange stripes all over the body One of the subjects developmental biologists are interested in is the development of pattern . There are the obvious externally visible patterns , the stripes of a zebra, leopard spots, the ordered ranks of your teeth, etc., etc., etc
  4. Blaschko's lines, also called the lines of Blaschko, named after Alfred Blaschko, are lines of normal cell development in the skin. [1] Nevus (or nevi if multiple) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. New!!
  5. Blaschko's lines mark the embryonic migration of ectodermal cells, with both melanocytes and keratinocytes arising from the ectoderm. Blaschko's lines are more wavy and whorled than the straight bands of dermatomes, which follow the distribution of cutaneous sensory nerves. Blaschko's lines become visible as a line of darker or.
  6. The skin abnormalities that define each stage occur along lines of embryonic and fetal skin development known as Blaschko's lines (see Figure 3). Blaschko's lines correspond with cell migration or growth pathways that are established during embryogenesis. Like dermatomes, they are linear on the limbs and circumferential on the trunk. Unlike.
  7. Blaschko Lines. Everyone is born with Blaschko lines, which are invisible lines that represent how the skin cells migrated during the development of a fetus. In people who have skin diseases, however, these lines in the skin become visible. This causes the appearance of unusual patterns on the face, limbs, and other parts of the body

Our Skin Is Covered With Invisible Stripes Mental Flos

2) and hyperpigmented macular lesions along Blaschko's lines (Stage 3). The lesions can be profuse or limited in number. Such lesions are highly diagnostic when they occur in a female neo-nate, have a predominant acral topography with a linear distri-bution on Blaschko's lines, and fade away spontaneously in earl 7. Blaschko's Lines. The lines of normal epidermal cell development in the skin are typically invisible. Nevertheless, these lines can become visible when diseases of the skin or mucosa manifest themselves according to the patterns. German dermatologist Dr. Alfred Blaschko first described the phenomenon in 1901 distributed along Blaschko lines, particularly visible after hair clipping. Th ese were characterised by linear, tightly adherent, exuberant, occasionally verrucous, hyperkeratotic, hyperpigmented plaques aff ecting the face, ears, trunk and legs. Th e nose and footpads were not aff ected. No pruritus was noticed. No general signs were observed Focal dermal hypoplasia is a genetically inherited disorder that can affect the development of many different organ systems and was first described by Goltz in 1962. It presents with characteristic abnormalities of the skin, eyes and teeth and may also have effects on the skeletal, gastrointestinal, genitourinary, neurological and.

Acne following Blaschko's lines in Proteus syndrome. There had been no visible skin changes in this area before appearance of acne, documented in clinical photographs obtained annually from age 11 to 13 years. He reported that the hair on the left side of his face was growing more rapidly than on the right side. He had left-sided. Acne following Blaschko's lines in Proteus syndrome Alexander M. Cartron, BS,a DeetiJ.Pithadia,MD,a Anna Buser, BS,b Leslie G. Biesecker, MD,b and Thomas N. Darling, MD, PhDa There had been no visible skin changes in this area before appearance of acne, documented in clinical photographs obtained annually from age 1 Alopecia due to scalp mosaicism is a feature of incontinentia pigmenti, where the areas of alopecia follow Blaschko's lines. Unlike this case, the involved areas are completely bald. In this case the scalp mosaicism produced a population of hair that differed from surrounding scalp because of the length and texture

Each person has stripes on their body called Blaschko's

In heterozygous females affected by an X-linked skin disorder, lesions often appear in a characteristic pattern, the so-called Blaschko's lines. We investigated a female Labrador Retriever and her crossbred daughter, which both showed similar clinical lesions that followed Blaschko's lines. The two male littermates of the affected daughter had died at birth, suggesting a monogenic X. For some females this can be seen in their skin as Blaschko's lines. A specific wavelength of UV light (I've tried to find out which wavelength but no dice so far, articles just mention UV or a certain wevelength without a number) can make them visible if they are there. In some females whose parents have very different skin coloration. low Blaschko's lines. (Blaschko's lines are patterns of lines on the skin that represent the developmental growth pattern of the skin during epidermal cell migration; these lines usually aren't visible but can be seen in patients with certain skin diseases.2) Li-chen striatus most frequently affects th Blaschko's lines are patterns of lines on the skin that represent the developmental growth pattern of the skin during epidermal cell migration; these lines usually aren't visible but can be seen in patients with certain skin diseases.(2). Lichen striatus most frequently affects the neck, trunk, and limbs; nail involvement is rare.(1).

Blaschko's Lines and Invisible Stripes on Human Skin

Our Skin Is Covered With Invisible Stripes

A synonym for Blaschko's lines is lines of Blaschko. Find more similar words at wordhippo.com Thomas et al. (1989) provided a diagram of Blaschko lines, which were first described by Blaschko (1901). On the basis of studies of linear skin diseases, Jackson (1976) reviewed Blaschko's work and reproduced some of the original drawings The theoretical paths of dorsal melanocytes, migrating laterally from the midline but stretched by the flexed fetus, is one potential basis for lines of normal cell development called Blaschko's lines. The lines appear V-shaped on the back, S-shaped on the chest, hourglass-shaped on the face, and swirled on the scalp

16 Things That Glow Under Black Light - ThoughtCo

1. level 1. wombatgal. 9 years ago · edited 9 years ago. They don't always appear as stripes. On some areas of the body, they like more like spots or swirls. Source: I have Incontinentia pigmenti, one of the disorders that can cause Blaschko's lines to become visible We report on a 22 year old man with hyperpigmentation distributed along the lines of Blaschko in whom cytogenetic analysis showed mosaicism for an unusual supernumerary marker chromosome. The patient was of normal intelligence and was not dysmorphic. The marker was present in 30% of his lymphocytes and in 6% of his skin fibroblasts from a dark area, while fibroblasts from a light area showed a.

Blaschko's Lines - Freethought Blog

  1. 15. Humans have stripes, we just normally can't see them. They're called Blaschko's lines and form along the paths of embryonic cell migration. The stripes are sort of U-shaped down our front, V-shaped on our back, wavy on the head and face and we have basic, simple stripes on our extremities
  2. (Blaschko's lines are patterns of lines on the skin that represent the developmental growth pattern of the skin during epidermal cell migration; these lines usually aren't visible but can be seen in patients with certain skin diseases. 2) Lichen striatus most frequently affects the neck, trunk, and limbs; nail involvement is rare. 1.
  3. YouTube Babies. October 14, 2017 ·. Humans have stripes, called Blaschko's Lines, that may be observed under a black or ultraviolet light. They don't glow so much as become visible

Blaschko's Lines by Rebecca Glenn - Prez

  1. Most strikingly, these linear areas and papular lesions formed a clearly visible pattern of Blaschko lines on her back . Findings in this child are summarized in the Table 1 (proband 6). The father of female proband 6 had some signs of the disorder in a limited distribution. He was regarded as having a postzygotic mutation leading to a mild.
  2. Press the red color button 25 times. Press the blue color button 25 times. This is a pretty straightforward process so if you have already installed the LED strips, all you have to do is press the remote. As you press the buttons on your remote control, your LED light strips will begin changing color until you get a desired blacklight color effect
  3. Cafe-au-lait spots: The general principle is that if you have a patient with more than 6 lesions, you have to consider neurofibromatosis and get into that whole thing. Lentiginosis and Blaschko's lines: Try to make a specific diagnosis so you can look for those hidden problems, and send the patients for a work-up
  4. Other embryonic development patterns besides X-inactivation can become visible though, revealing Blaschko's lines and producing partially or completely tiger-striped humans. This requires a mutation in a pigment-producing gene very early on and the mutant and non-mutant cells get folded together like a paint mixer during normal development
  5. Segmental vitiligo. Segmental vitiligo is a subtype of vitiligo characterized by depigmented macules or patches arranged in a patterned distribution that is refractory to medical treatment but excellent response to surgical treatment 1).. Vitiligo is an acquired disorder characterized by depigmented macules or patches on the skin due to the loss of functional melanocytes

Typical hyperpigmentation along Blaschko's lines fading in adolescence (+++) (Stage 3) Linear, atrophic, hairless lesions on limbs (Stage 4) or scarring alopecia of the vertex (Stages 3 or 4) Teeth: dental agenesis (hypodontia or oligodontia), shape anomalies (peg-shaped incisors, conical teeth, molar cusp pattern alteration) and delayed eruptio macules and linear streaks arranged along the line of Blaschko on extensor aspects of both lower limb and upper limb were seen. In between the hyperpigmented streaks, multiple hypopigmented macules are also present. The overlying skin was normal and no clinical sign suggestive of Koebner phenomenon was visible. All routine investigations were. Case Discussion. Lichen striatus (B) is a well-described inflammatory dermatosis seen in children, which typically occurs within lines of embryological skin development called Blaschko's lines Hypopigmented macules and papules following the lines of Blaschko: a novel variant of Darier's disease Vincenzo Maione, MD Editor, Laure Dehen, MD A 25-year-old, otherwise healthy man consulted us with Celeste Lebbe, MD regarding the complaint of multiple pruritic white spots on the Department of Dermatology trunk Smart News Keeping you current Why Pantone's Color of the Year Is the Shade of Science PANTONE 18-3838 Ultra Violet is a deep saturated purple, but it doesn't hold a candle to true ultraviole

However, the stripes are decidedly visible if you are suffering from a number of skin diseases. Now, there are a number of scientific explanations as to how they came to be. So, in this article, we'll cover the history and discovery of these skin lines, what they mean, and possible treatment for the skin ailments. What are Blaschko's lines While Blaschko Lines sound like a cheat - We have stripes! But they're invisible. - but there are some dramatic examples of them. Humans with chimerism can show them dramatically

Human skin is covered in stripes of different colours only

Those lines represent epidermal cell migration and proliferation of embryonal development. Normally invisible, they only become manifest in a few skin diseases . We hypothesize that, in the context of typical skin changes, visible Blaschko lines on the teeth in the form of vertical grooves are almost pathognomonic for FDH It has been postulated that cells of Blaschko lines, as part of skin mosaicism, become visible when stimulated by type 1 interferon (alpha and beta) chemokines (8). Upregulation of type 1 interferon-inducible genes has also been found in cGVHD monocytes (9) Blaschko's lines were discovered in 1901, and medical professionals still use them in diagnoses and surgery. While typically invisible, these lines can become visible when diseases of the skin. Lines of inquiry: mosaicism causes these unusual pigmented patterns called Blaschko's lines. including V-shaped streaks on the back that are sometimes only visible under ultraviolet light..

Blaschko lines - Altmeyers Encyclopedia - Department

Follows Blaschko's lines; Streaks and whorls; Fades in adolescence; The third incontinentia pigmenti stage is the hyperpigmented stage in which the skin is darkened in a swirled pattern often described as a marble cake appearance. In some patients, the adjacent areas ultimately thin and widen leaving streaky hypopigmentation Blaschko's lines: strange stripes all over the body. Blaschko's lines are an extremely rare and unexplained phenomenon of human anatomy first presented in 1901 by German dermatologist Alfred Blaschko. The most common, visible signs of infection are excessively enlarged arms, legs, genitalia, and breasts Blaschko's lines are skin lines that form patterns that are though to be the result of the migration of embryonic cells as we form in utero. They are not visible at all under normal conditions, but some diseases can make them apparent. This creates a strange, marble-cake like look to the skin and a V shape will become apparent on the back. Lichen striatus is not a lethal skin condition but can be troubling due to the beginning of visible rashes along the lines of Blaschko. The beginning can be uninviting and it can be itchy for some although the disease is typically asymptomatic. It normally deals with without a need for treatment other than in cases where the rashes are itchy.

In an article on lines of Blaschko, 1 the authors referred to a study of pigmentary lines by Selmanowitz and me 2 and pointed out that we thought that those lines did not correspond to lines of Blaschko. We did say that in the article; however, after looking at the diagrams provided by Bolognia et al, 1 it is clear to me that these pigmentary lines did indeed follow Blaschko lines 15) Tiger (Blaschko's Lines) Blaschko's lines are actually a skin condition we all have. They're lines along which epidermal cells migrate in the fetus. Most of the time, however, they're completely invisible. When they do show, there's another disorder at the root of it Blaschko's lines, which may reflect an embryological development.6-11 However, whether the distribution of linear morphoea is in keeping with the lines of Blaschko has been discussed controversially. 12,13 In this study we assessed a cohort of paediatric patients with linea This can lead to visible changes, such as patches of colored skin or hair, or localized diseases. In humans it can be possible to see stripes (called Blaschko's lines) that occur when two colored cell types develop together. Occasionally it happens that two embryos in a womb will fuse at an early stage of development. The cells of the two.

Birthmarks or Pathology? - MEDizzy Journal

(Humans do actually have stripes caled Blaschko's lines that are only visible in the ultraviolet spectrum) January 24, 2021 (2:03 pm) 182 notes # danny phantom # danny fenton # sam manson # tucker foley # quasar draws # blaschko's lines # fanart # basically its what you'd see in the ultraviolet spectru Somatic mosaicism for KRT1 and KRT10 mutations causes epidermolytic epidermal nevi, which are blistering and hyperkeratotic lesions limited to certain areas of the skin, and often following Blaschko's lines (linear epidermolytic hyperkeratotic nevus). In somatic mosaicism, the mutation of the gene occurs after fertilization and is not inherited Some Imperial geneticists have proposed that the striped coloration of the Ziadd represent a variation of the usually invisible Blaschko's lines found in homo sapiens and may have been a recessive trait already present in Terran Neanderthals, similar to albinism. The question is currently unresolved. 4. Vlazhdumect Blaschko′s Lines. Blaschko′s lines are imaginary skin lines which various skin conditions are known to follow. They do not follow neural, vascular, or lymphatic structures and are distinct from dermatomes as well as Langer′s lines. These were first described by Alfred Blaschko in 1901. The most widely accepted basis for these lines is. 16. Humans have stripes, we just normally can't see them. They're called Blaschko's lines and form along the paths of embryonic cell migration. The stripes are sort of U-shaped down our front, V-shaped on our back, wavy on the head and face and we have basic, simple stripes on our extremities

Skin pigmentary anomalies and mosaicism for an acentric

Blaschko's lines are an extremely rare and unexplained phenomenon of human anatomy first presented in 1901 by German dermatologist Alfred Blaschko. Neither a specific disease nor a predictable symptom of a disease, Blaschko's lines are an invisible pattern built into human DNA Phylloid hypomelanosis and pigmentary mosaicism of the Ito type (hypomelanosis of Ito) is clearly different because the distribution of Blaschko's lines and the phylloid pattern is dissimilar, as shown by Molho-Pessach et al[ 6]. González-Enseñat et al[ 28] insist that a hypopigmented phylloid pattern indicates the presence of a specific. There is some debate whether it is a distinct entity or a primary atrophic morphea. 10 Linear atrophoderma of Moulin has a similar morphology with hyperpigmented depressions and cliff-drop borders, but these lesions follow the lines of Blaschko. 11 Linear morphea initially can present as a linear erythematous streak but more commonly appears.

Multiple seborrheic keratoses arranged along Blaschko's lines have been suggested to reflect genetic mosaicism . Livingstone et al. described a 76-year-old woman who had since birth multiple seborrheic keratosis-like lesions arranged in a systematized linear pattern on the left side of her body (Fig. 7.21). Some years ago, a squamous cell. The Blaschko lines become visible in several cutaneous disorders and are thought to reflect the migration of the neuroectoderm during embryogenesis. Although resembling dermatoms, they are more whorled and show a distinct distribution with a steeper course on the back This lesion is an example of cutaneous mosaicism (p. 343) and so tends to follow Blaschko's lines (Figure 20.9). Keratinocytes in these lines of wart-like growth are genetically different from their normal appearing neighbours. Keratolytics (Formulary 1, p. 401) lessen the roughness of some and small epidermal naevi may be excised Humans have stripes, we just normally can't see them. They're called Blaschko's lines and form along the paths of embryonic cell migration. The stripes are sort of U-shaped down our front, V-shaped on our back, wavy on the head and face and we have basic, simple stripes on our extremities. LadySygerrik , pexels Repor

Humans Have Invisible Stripes On Their Skin That Are

Along this line, authoritative reviews on SVD have been published.1-3 Here, we would like to extend current con-cepts of SVD by highlighting a molecular pathway that seems to be involved in several well-defined SVD, some of which The Blaschko lines become visible in sev-. Visible light is composed of photons in the energy range of around 2 to 3 eV (Fig. 3). As the energy of the light increases, the wavelength decreases. Orange light with a wavelength of 620 nanometers is composed of photons with energy of 2 eV. It is the energy range of 1.8 to 3.1 eV which triggers the photo receptors in the eye Most of the lesions usually follow the Blaschko's lines. The lines of Blaschko represents the developmental growth pattern during epidermal cell migration. They are not in relation to any nervous, vascular or lymphatic structures. Typically, these lines are not visible; however, certain inherited and acquired diseases of the skin follow them

Understanding Genetic

Incontinentia pigmenti. An X-linked syndromic muti-systemic ectodermal dysplasia presenting neonatally in females with a bullous rash along Blaschko's lines (BL) followed by verrucous plaques and hyperpigmented swirling patterns. It is further characterized by teeth abnormalities, alopecia, nail dystrophy and can affect the retinal and the. Pattern analysis of skin lesions is an art and a key competence of every dermatologist. Three major line patterns cover the human body—the dermatomes or Head zones, the nevoid lines of Blaschko, and the relaxed skin tension lines, or Langer lines. Head zones represent skin areas innervated from the same sensory neuronal segment or spinal nerve zone Blaschko's lines pattern of distribution of skin lesions or pigmentary anomalies, linear on the extremities, S-shaped curves on the abdomen, and V-shaped on the back; thought to result from genetic mosaicism and interplay of transverse clonal proliferation and longitudinal growth and flexion of the embry Imaging lines represent a pattern followed by many skin disorders. It is named after Alfred Blaschko (1858-1922), (Fig. 2), a German dermatologist. Lines of Blaschko [1,9] Figure 2. Alfred Blaschko (1858-1922)

Blaschko's Lines SpringerLin

Trypophobia Test, Cure and Causes (Fear of Holes in Skin) Take Trypophobia test and cure it through behavioral or cognitive therapies. Trypo-phobia (fear of holes in the skin) is caused by psychological conditions. Trypophobia is a peculiar fear of holes that a few individuals have. They are anxious about the possibility that they will fall. Pigmentary demarcation lines (PDL), also known as Futcher lines or Voigt lines. Physiological (natural) abrupt transition lines from areas of deeper skin color to areas with lighter color. They present sharp demarcation lines that occur on different parts of the body Brindled pigmentation and patches of hairless skin are visible. The hairless skin probably represents scarring alopecia following the different stages of skin lesions described. The patterns of hyperpigmentation and the skin alterations follow the lines of Blaschko. The depicted horse corresponds to animal III-10 in the pedigree shown in Figure 2 follows the lines of Blaschko, as in our patient. The lines of Blaschko consist of transverse bands on the trunk, following a sigmoid curve over the abdomen, a V shaped curve over the back,and showing a marked midline eVect.On the limbs they follow a perpendicular pattern and on the scalp they form a spiral. It is now well known that Blaschko. In heterozygous females, cells with the inactivated X-chromosome carrying the pathogenic variant give rise to normal skin, whereas inactivation of the wild-type X-chromosome results in skin lesions. This leads to a visible functional mosaicism with patches of normal or lesioned skin following the lines of Blaschko (Happle 2006; Happle 2016)

Focal dermal hypoplasia (Goltz Syndrome): A crossCODE TRUNK Visible Penis Line Short | Nasty Pig Fetish andadobe photoshop - Techniques and suggestions for drawing

Talk:Blaschko's lines - Wikipedi

Hypomelanosis of Ito. Hypomelanosis of Ito also called incontinentia pigmenti achromians, is a very rare birth defect that causes streaked, whirled, or mottled patches of light-colored (hypopigmented) skin 1).Hypomelanosis of Ito is part of a rare genetic neurocutaneous syndrome 2).These skin changes often develop within the first two years of life In the United States 1.4 million children were maltreated in 1988, resulting in an estimated 2000 to 5000 deaths.[1][1]Largely due to the rising awareness and sensitivity to the horrors of child abuse, the number of deaths declined to approximately 1500 in 1993.[2][2] Guidelines have been published to aid in the identification and management of child maltreatment,[3][3] and reporting of all. The lesions have a linear distribution following Blaschko's lines. Pityriasis lichenoides is an uncommon benign skin disorder with two major variants: acute and chronic.Herein, we report the case of an 11-year-old girl with concurrent pityriasisli chenoides chronica and lichen striatus, a previously unreported association The lesions usually present at birth or in childhood. We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body. Keywords: Blaschko′s lines, nevus, porokeratoti

Blaschko's lines, also called the lines of Blaschko, named after Alfred Blaschko, are lines of normal cell development in the skin.These lines are invisible under normal conditions. They become apparent when some diseases of the skin or mucosa manifest themselves according to these patterns Papular epidermal nevus with skyline basal cell layer (PENS), a variant of epidermal nevi, has recently been described as a small, round or polygonal papule, visible at birth or shortly thereafter, with characteristic histopathologic features. It has been considered a separate entity from keratinocytic nevi because no lesion observed thus far has followed any of the known archetypical. Blaschko's lines are imaginary skin lines which various skin conditions are known to follow. They do not follow neural, vascular, or lymphatic structures and are distinct from dermatomes as well as Langer's lines.[1] These were first described by Alfred Blaschko in 1901. The most widely accepted basis for these lines is genotypic mosaicism, i.e.